DivA-BE manuscript published and a fond farewell to Carley!!

Carley’s DivA-BE manuscript was published in Nucleic Acids Research! Congratulations to her and all of the authors! The work characterizes the editing activity for a several diversifying base editors that produce C-to-N mutations. The study also establishes a more efficacious Diversifying AID fusion Base Editor, or DivA-BE for short. We recommend this editor for high-throughput studies identifying variants with an effect on cellular phenotype or engineering proteins in situ. The construct is available on Addgene!

It was also Carley’s last week in the lab! She will be starting her Ph.D at the Interdisciplinary Doctoral Training Program at Medical College of Wisoncsin this Fall. We will miss her, but we so excited for her next steps!